Preventing DCA’s Negative Effects: Tools and Supplements

Posted on 30 December 2018 Supplements and other methods to avoid DCA’s negative effects


You should take a supplement with preventive effects before starting a Sodium dichloroacetate program. The risk of developing reversible peripheral neuropathy and other nervous system responses may be reduced in this manner.

Find below a list of substances that are either required or highly recommended for a positive DCA experience with little potential for negative outcomes.

Thiamine, or vitamin B1.


(It’s essential that you do this) (every other day, take half a 100mg capsule or pill. To be taken in the morning and again before lunch.

Another option is to divide the 100 mg dose into three daily doses. Amounting to 300 milligrams altogether


Thiamine, a member of the B vitamin family, seems to provide some protection against peripheral neuropathy. This dietary supplement is effective for treating neuropathies brought on by both diabetes and heavy alcohol consumption, in addition to DCA-induced neuropathy. (Ref.)

Benfotiamine is recommended since it is absorbed more than five times better than regular thiamine.


Furthermore, recent studies suggest that vitamin B1 may inhibit the proliferation of cancer cells. (Ref.)


Take one 300 mg R+/S- capsule/tablet or one 150 mg R+ capsule/tablet three times day of alpha-lipoic acid (Necessary). It should be taken in the morning, during lunch, and before supper. To sum it up: 900 mg (R+/S-) or 450 mg (R+).


The powerful antioxidant alpha-lipoic acid aids in the prevention and management of neuropathy. The supplement helps ease nervousness and cognitive issues, and it can aid in avoiding peripheral neuropathy’s uncomfortable symptoms including tingling, burning, painful feelings, and numbness. (Ref.)


When consuming R-form a-Lipoic acid, lower dosages are sufficient.

You need to take twice as much Racemate -Lipoic acid (a combination of the R and L types) to get the same benefits.


If you are undergoing radiation or chemotherapy, you should not take alpha-lipoic acid.

Because of its powerful antioxidative impact, alpha-lipoic acid may reduce the efficacy of chemotherapy. We advise against using this supplement a few days before to chemotherapy, during chemotherapy, and for a week afterwards. (Ref.)


The radioprotective effects of alpha-lipoic acid have been shown. That’s why you shouldn’t take it for at least a few days leading up to, during, and two weeks following these treatments.

a-L-Carnitine Acetyl. (Recommended)


(three times day, take one 600mg pill or tablet. It should be taken in the morning, during lunch, and before supper. In sum, 1800 milligrams)


Carnitine, according to the vast majority of scientific research, may help alleviate peripheral neuropathy. Acetyl L-Carnitine is also desirable since it has no negative health effects and may be used safely over the long term. Multiple references (1, 2) (Ref3.)


Both -lipoic acid and acetyl L-carnitine are effective, but together they seem to have a synergistic impact in warding off neuropathy.

Sodium dichloroacetate may sometimes cause stomach upset and sickness. If this is the case, you may find that taking DCA after consuming even a little meal and some water helps calm your stomach.


If it didn’t work, you may try taking proton pump inhibitors, which work by decreasing the amount of stomach acid produced.


As long as there aren’t any significant disparities between them, all PPIs are OK.

Indicated by the symbol “P.” for pantoprazole.

(daily, at the same time, take one 40mg pill. Take it half an hour before eating and before taking DCA.


Given that Pantoprazole does not appear to have any negative interactions with other medications, it is recommended for use.


Do not continue taking DCA if you notice any moderate side effects or if you develop a severe form of peripheral polyneuropathy.


In all cases, the negative effects of sodium dichloroacetate can be reversed.

Most of the negative effects of stopping DCA use typically subside after a few days. In some cases, peripheral neuropathy may take longer than a week to improve. (Ref.)

The levels of tumor markers in the blood serum should also be monitored regularly if this is possible.


Imaging tests like ultrasounds, CT scans, MRIs, and PET scans can tell doctors more about the state of your health and the progression of any diseases you may have, especially cancer.


By suzzy, this entry was posted in Other. Add this link to your bookmarks!